SOX10 is widely expressed in normal human tissues including melanocytes and breast tissue. SOX10 is also an important marker in malignant tumors such as melanoma, breast carcinoma, gliomas, and benign tumors such as schwannomas.SOX-10 is considered as a very reliable marker for recognizing residual desmoplastic melanomas. In normal tissues, it is expressed in Schwann cells, melanocytes and myoepithelial cells ofsalivary, bronchial and mammary glands. SOX-10 expression is also observed in mast cells.
SOX10 (Melanoma Marker)
SKU: Mob565-
Categories: IVD - For U.S. Market, IVD - Outside U.S. Market, Primary Antibodies
Tags: Concentrated, Ready to Use, S
Description
Additional information
| Catalog No. | Mob565 Concentrated, PDM565 Prediluted |
|---|---|
| Clone | 20B7 |
| Isotype | IgG1 |
| Immunogen | Human SOX10 recombinant protein |
| Species | Mouse |
| Cellular Localization | Nuclear |
| Positive Control Tissue | Melanoma |
| Pretreatment | Citrate Buffer pH 6.0 |
| Incubation & Temperature | 30 min @ RT |
| Intended Use | IVD |
| Detection System | PolyVue Plus – Two Step Detection System or Montage PolyVue Plus Auto Detection System for Montage 360 System |
| Description/Type | Mouse Monoclonal Antibody |
| Format | Tissue Culture Supernatant |
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